|
|
L-arginine + pyruvate <=> 5-guanidino-2-oxopentanoate + L-alanine
|
2.6.1.40
(R)-3-amino-2-methylpropionate---pyruvate transaminase
2.6.1.51
serine---pyruvate transaminase
2.6.1.84
arginine---pyruvate transaminase
|
–
–
–
|
|
BRENDA:
BR48810
KEGG:
R08197
MetaCyc:
RXN-8956
|
|
|
|
L-arginine + 2-oxoglutarate <=> L-glutamate + 5-guanidino-2-oxopentanoate
|
2.6.1
2.6.1.42
branched-chain-amino-acid transaminase
|
–
–
|
|
BRENDA:
BS356596
MetaCyc:
RXN-7564
SABIO-RK:
13596
|
|
|
|
ATP + L-glutamine + HCO3- + H2O <=> L-glutamate + Carbamoyl_phosphate + ADP + phosphate + H+
|
6.3.4.16
carbamoyl-phosphate synthase (ammonia)
6.3.5.5
carbamoyl-phosphate synthase (glutamine-hydrolysing)
|
–
–
|
|
BRENDA:
BR152
KEGG:
R00575
MetaCyc:
CARBPSYN-RXN
SABIO-RK:
203
|
|
|
|
N-acetyl-L-glutamate_5-semialdehyde + NADP+ + phosphate <=> H+ + N-acetyl-L-glutamyl_5-phosphate + NADPH
|
1.2.1.38
N-acetyl-gamma-glutamyl-phosphate reductase
|
–
|
|
BRENDA:
BR36780
KEGG:
R03443
MetaCyc:
N-ACETYLGLUTPREDUCT-RXN
|
|
|
|
N-acetyl-L-glutamate + ATP <=> N-acetyl-L-glutamyl_5-phosphate + ADP
|
2.7.2.8
acetylglutamate kinase
|
–
|
|
BRENDA:
BR47830
KEGG:
R02649
MetaCyc:
ACETYLGLUTKIN-RXN
SABIO-RK:
2545
|
|
|
|
L-ornithine <=> L-proline + NH3
|
4.3.1.12
ornithine cyclodeaminase
|
–
|
|
BRENDA:
BR3424
KEGG:
R00671
MetaCyc:
ORNITHINE-CYCLODEAMINASE-RXN
SABIO-RK:
1051
|
|
|
|
L-glutamate + acetyl-CoA <=> H+ + N-acetyl-L-glutamate + CoA
|
2.3.1.1
amino-acid N-acetyltransferase
2.3.1.17
aspartate N-acetyltransferase
2.3.1.183
phosphinothricin acetyltransferase
2.7.2.8
acetylglutamate kinase
6.3.4.16
carbamoyl-phosphate synthase (ammonia)
|
–
–
–
–
–
|
|
BRENDA:
BR43962
KEGG:
R00259
MetaCyc:
N-ACETYLTRANSFER-RXN
SABIO-RK:
764
|
|
|
|
L-arginine + O2 <=> 4-Guanidinobutanamide + CO2 + H2O
|
1.13.12.1
arginine 2-monooxygenase
1.13.12.2
lysine 2-monooxygenase
|
–
–
|
|
BRENDA:
BR40466
KEGG:
R00559
MetaCyc:
ARGININE-2-MONOOXYGENASE-RXN
|
|
|
|
N2-succinyl-L-ornithine + 2-oxoglutarate <=> L-glutamate + N-succinyl-L-glutamate_5-semialdehyde
|
2.6.1.11
acetylornithine transaminase
2.6.1.81
succinylornithine transaminase
|
–
–
|
|
BRENDA:
BR48672
KEGG:
R04217
MetaCyc:
SUCCORNTRANSAM-RXN
|
|
|
|
H+ + 5-guanidino-2-oxopentanoate <=> CO2 + 4-guanidinobutyraldehyde
|
4.1.1.75
5-guanidino-2-oxopentanoate decarboxylase
|
–
|
|
BRENDA:
BR336
KEGG:
R03178
MetaCyc:
4.1.1.75-RXN
|
|
|
|
N-succinyl-L-glutamate_5-semialdehyde + NAD+ + H2O <=> N2-succinylglutamate + NADH + H+
|
1.2.1.71
succinylglutamate-semialdehyde dehydrogenase
|
–
|
|
BRENDA:
BR48653
KEGG:
R05049
MetaCyc:
SUCCGLUALDDEHYD-RXN
|
|
|
|
L-glutamate + ATP <=> L-5-glutamyl_phosphate + ADP
|
2.7.2.11
glutamate 5-kinase
|
–
|
|
BRENDA:
BR47821
KEGG:
R00239
MetaCyc:
GLUTKIN-RXN
SABIO-RK:
752
|
|
|
|
H2O + L-arginine <=> Urea + L-ornithine
|
3.5.3.1
arginase
3.5.3.7
guanidinobutyrase
|
–
–
|
|
BRENDA:
BR19260;
BS140960
KEGG:
R00551
MetaCyc:
ARGINASE-RXN
SABIO-RK:
574
|
|
|
|
H2O + L-arginine <=> NH3 + L-citrulline
|
3.5.3.15
protein-arginine deiminase
3.5.3.6
arginine deiminase
|
–
–
|
|
BRENDA:
BR22730;
BS369889
KEGG:
R00552
MetaCyc:
ARGININE-DEIMINASE-RXN
SABIO-RK:
97
|
|
|
|
4-Guanidinobutyrate + H2O <=> 4-aminobutanoate + Urea
|
3.5.3.10
D-arginase
3.5.3.17
guanidinopropionase
3.5.3.2
guanidinoacetase
3.5.3.7
guanidinobutyrase
|
–
–
–
–
|
|
BRENDA:
BR22731
KEGG:
R01990
MetaCyc:
GUANIDINOBUTYRASE-RXN
SABIO-RK:
2030
|
|
|
|
N2-Acetyl-L-ornithine + H2O <=> L-ornithine + acetate
|
2.3.1.35
glutamate N-acetyltransferase
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
3.5.1.16
acetylornithine deacetylase
3.5.1.17
acyl-lysine deacylase
3.5.1.B4
|
–
–
–
–
–
|
|
BRENDA:
BR19236
KEGG:
R00669
MetaCyc:
ACETYLORNDEACET-RXN
SABIO-RK:
1049
|
|
|
|
N-acetyl-L-citrulline + H2O <=> L-citrulline + acetate
|
3.5.1.16
acetylornithine deacetylase
3.5.1.B4
|
–
–
|
|
BRENDA:
BR48939;
BS394032
KEGG:
R09107
MetaCyc:
RXN-7933
|
|
|
|
H+ + N2-succinyl-L-arginine + H2O <=> NH3 + N2-succinyl-L-ornithine + CO2
|
3.5.3.23
N-succinylarginine dihydrolase
|
–
|
|
BRENDA:
BR48703
KEGG:
R04189
MetaCyc:
SUCCARGDIHYDRO-RXN
|
|
|
|
4-guanidinobutyraldehyde + NAD+ + H2O <=> 4-Guanidinobutyrate + NADH + H+
|
1.2.1.19
aminobutyraldehyde dehydrogenase
1.2.1.3
aldehyde dehydrogenase (NAD+)
1.2.1.54
gamma-guanidinobutyraldehyde dehydrogenase
1.2.1.8
betaine-aldehyde dehydrogenase
|
–
–
–
–
|
|
BRENDA:
BR29413
KEGG:
R03177
MetaCyc:
1.2.1.54-RXN
SABIO-RK:
3007
|
|
|
|
L-arginine + succinyl-CoA <=> H+ + N2-succinyl-L-arginine + CoA
|
2.3.1.109
arginine N-succinyltransferase
|
–
|
|
BRENDA:
BR43973
KEGG:
R00832
MetaCyc:
ARGININE-N-SUCCINYLTRANSFERASE-RXN
|
|
|
|
L-arginine + H2O + O2 <=> 5-guanidino-2-oxopentanoate + NH3 + H2O2
|
1.4.3.14
L-lysine oxidase
1.4.3.2
L-amino-acid oxidase
1.4.3.25
L-arginine oxidase
|
–
–
–
|
|
BRENDA:
BR51927
KEGG:
R11604
MetaCyc:
ARG-OXIDATION-RXN
SABIO-RK:
968
|
|
|
|
N2-succinylglutamate + H2O <=> L-glutamate + succinate
|
3.5.1.96
succinylglutamate desuccinylase
|
–
|
|
BRENDA:
BR48702
KEGG:
R00411
MetaCyc:
SUCCGLUDESUCC-RXN
|
|
|
|
N2-Acetyl-L-ornithine + Carbamoyl_phosphate <=> H+ + N-acetyl-L-citrulline + phosphate
|
2.1.3.11
N-succinylornithine carbamoyltransferase
2.1.3.9
N-acetylornithine carbamoyltransferase
|
–
–
|
|
BRENDA:
BR48711
KEGG:
R07245
MetaCyc:
2.1.3.9-RXN
|
|
|
|
argininosuccinate <=> L-arginine + fumarate
|
4.3.2.1
argininosuccinate lyase
4.3.2.2
adenylosuccinate lyase
|
–
–
|
|
BRENDA:
BR3431
KEGG:
R01086
MetaCyc:
ARGSUCCINLYA-RXN
SABIO-RK:
573
|
|
|
|
ATP + L-arginine + tRNAMet <=> AMP + diphosphate + L-arginyl-tRNAArg
|
6.1.1.19
arginine---tRNA ligase
6.1.1.6
lysine---tRNA ligase
|
–
–
|
|
BRENDA:
BR49
KEGG:
R03646
SABIO-RK:
407
|
|
|
|
L-glutamate_5-semialdehyde + phosphate + NADP+ <=> L-5-glutamyl_phosphate + NADPH + H+
|
1.2.1.41
glutamate-5-semialdehyde dehydrogenase
|
–
|
|
BRENDA:
BR36782
KEGG:
R03313
MetaCyc:
GLUTSEMIALDEHYDROG-RXN
SABIO-RK:
3127
|
|
|
|
L-arginine + 2-oxoglutarate + O2 <=> (2S,3S)-3-hydroxyarginine + succinate + CO2
|
1.14.11.41
L-arginine hydroxylase
|
–
|
|
BRENDA:
BR50571
KEGG:
R09363
MetaCyc:
RXN-14542
|
|
|
|
N2-Acetyl-L-ornithine + 2-oxoglutarate <=> L-glutamate + N-acetyl-L-glutamate_5-semialdehyde
|
2.6.1.11
acetylornithine transaminase
2.6.1.13
ornithine aminotransferase
|
–
–
|
|
BRENDA:
BR48055
KEGG:
R02283
MetaCyc:
ACETYLORNTRANSAM-RXN
SABIO-RK:
2248
|
|
|
|
L-glutamate + N2-Acetyl-L-ornithine <=> N-acetyl-L-glutamate + L-ornithine
|
2.3.1.35
glutamate N-acetyltransferase
|
–
|
|
BRENDA:
BR44035
KEGG:
R02282
MetaCyc:
GLUTAMATE-N-ACETYLTRANSFERASE-RXN
SABIO-RK:
2247
|
|