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arginine metabolism

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
L-arginine + pyruvate <=> 5-guanidino-2-oxopentanoate + L-alanine 2.6.1.40 (R)-3-amino-2-methylpropionate---pyruvate transaminase
2.6.1.51 serine---pyruvate transaminase
2.6.1.84 arginine---pyruvate transaminase



L-arginine + 2-oxoglutarate <=> L-glutamate + 5-guanidino-2-oxopentanoate 2.6.1
2.6.1.42 branched-chain-amino-acid transaminase


ATP + L-glutamine + HCO3- + H2O <=> L-glutamate + Carbamoyl_phosphate + ADP + phosphate + H+ 6.3.4.16 carbamoyl-phosphate synthase (ammonia)
6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing)


N-acetyl-L-glutamate_5-semialdehyde + NADP+ + phosphate <=> H+ + N-acetyl-L-glutamyl_5-phosphate + NADPH 1.2.1.38 N-acetyl-gamma-glutamyl-phosphate reductase

N-acetyl-L-glutamate + ATP <=> N-acetyl-L-glutamyl_5-phosphate + ADP 2.7.2.8 acetylglutamate kinase

L-ornithine <=> L-proline + NH3 4.3.1.12 ornithine cyclodeaminase

L-glutamate + acetyl-CoA <=> H+ + N-acetyl-L-glutamate + CoA 2.3.1.1 amino-acid N-acetyltransferase
2.3.1.17 aspartate N-acetyltransferase
2.3.1.183 phosphinothricin acetyltransferase
2.7.2.8 acetylglutamate kinase
6.3.4.16 carbamoyl-phosphate synthase (ammonia)





L-arginine + O2 <=> 4-Guanidinobutanamide + CO2 + H2O 1.13.12.1 arginine 2-monooxygenase
1.13.12.2 lysine 2-monooxygenase


N2-succinyl-L-ornithine + 2-oxoglutarate <=> L-glutamate + N-succinyl-L-glutamate_5-semialdehyde 2.6.1.11 acetylornithine transaminase
2.6.1.81 succinylornithine transaminase


H+ + 5-guanidino-2-oxopentanoate <=> CO2 + 4-guanidinobutyraldehyde 4.1.1.75 5-guanidino-2-oxopentanoate decarboxylase

N-succinyl-L-glutamate_5-semialdehyde + NAD+ + H2O <=> N2-succinylglutamate + NADH + H+ 1.2.1.71 succinylglutamate-semialdehyde dehydrogenase

L-glutamate + ATP <=> L-5-glutamyl_phosphate + ADP 2.7.2.11 glutamate 5-kinase

H2O + L-arginine <=> Urea + L-ornithine 3.5.3.1 arginase
3.5.3.7 guanidinobutyrase


H2O + L-arginine <=> NH3 + L-citrulline 3.5.3.15 protein-arginine deiminase
3.5.3.6 arginine deiminase


4-Guanidinobutyrate + H2O <=> 4-aminobutanoate + Urea 3.5.3.10 D-arginase
3.5.3.17 guanidinopropionase
3.5.3.2 guanidinoacetase
3.5.3.7 guanidinobutyrase




N2-Acetyl-L-ornithine + H2O <=> L-ornithine + acetate 2.3.1.35 glutamate N-acetyltransferase
3.5.1.14 N-acyl-aliphatic-L-amino acid amidohydrolase
3.5.1.16 acetylornithine deacetylase
3.5.1.17 acyl-lysine deacylase
3.5.1.B4





N-acetyl-L-citrulline + H2O <=> L-citrulline + acetate 3.5.1.16 acetylornithine deacetylase
3.5.1.B4


H+ + N2-succinyl-L-arginine + H2O <=> NH3 + N2-succinyl-L-ornithine + CO2 3.5.3.23 N-succinylarginine dihydrolase

4-guanidinobutyraldehyde + NAD+ + H2O <=> 4-Guanidinobutyrate + NADH + H+ 1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.3 aldehyde dehydrogenase (NAD+)
1.2.1.54 gamma-guanidinobutyraldehyde dehydrogenase
1.2.1.8 betaine-aldehyde dehydrogenase




L-arginine + succinyl-CoA <=> H+ + N2-succinyl-L-arginine + CoA 2.3.1.109 arginine N-succinyltransferase

L-arginine + H2O + O2 <=> 5-guanidino-2-oxopentanoate + NH3 + H2O2 1.4.3.14 L-lysine oxidase
1.4.3.2 L-amino-acid oxidase
1.4.3.25 L-arginine oxidase



N2-succinylglutamate + H2O <=> L-glutamate + succinate 3.5.1.96 succinylglutamate desuccinylase

N2-Acetyl-L-ornithine + Carbamoyl_phosphate <=> H+ + N-acetyl-L-citrulline + phosphate 2.1.3.11 N-succinylornithine carbamoyltransferase
2.1.3.9 N-acetylornithine carbamoyltransferase


argininosuccinate <=> L-arginine + fumarate 4.3.2.1 argininosuccinate lyase
4.3.2.2 adenylosuccinate lyase


ATP + L-arginine + tRNAMet <=> AMP + diphosphate + L-arginyl-tRNAArg 6.1.1.19 arginine---tRNA ligase
6.1.1.6 lysine---tRNA ligase


L-glutamate_5-semialdehyde + phosphate + NADP+ <=> L-5-glutamyl_phosphate + NADPH + H+ 1.2.1.41 glutamate-5-semialdehyde dehydrogenase

L-arginine + 2-oxoglutarate + O2 <=> (2S,3S)-3-hydroxyarginine + succinate + CO2 1.14.11.41 L-arginine hydroxylase

N2-Acetyl-L-ornithine + 2-oxoglutarate <=> L-glutamate + N-acetyl-L-glutamate_5-semialdehyde 2.6.1.11 acetylornithine transaminase
2.6.1.13 ornithine aminotransferase


L-glutamate + N2-Acetyl-L-ornithine <=> N-acetyl-L-glutamate + L-ornithine 2.3.1.35 glutamate N-acetyltransferase

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